This includes jobs in human resources and engineering divisions
Microsoft is cutting 10,000 workers - almost 5% of its global workforce.
In another massive blow to the tech industry, the multi-million dollar company, which employs around 3,500 people in Ireland.
This could lead to around 175 job losses at its Leixlip and Leopardstown offices, where 3,500 people are employed.
This includes jobs in human resources and engineering divisions.
The software and PC giant laid off a small number of employees in July last year.
After sales plummeted for Windows and Microsoft devices, Microsoft is working to maintain growth rates at its cloud unit Azure.
In a note to staff, the company chairman thanked employees and said Microsoft will continue to hire in certain departments.

Saint Vincent De Paul Says Need For Help “Soaring” As Families Struggle To Afford Christmas
Kildare District Heating Studies Underway As Ireland Plans Major National Rollout
Government To Replace Apartment Planning Guidelines After Challenge Involving Clane-Maynooth Cllr
Sarto Road Locals In Naas Say They've Been Left In Dark Over Plan To Build Homes On Their Green Space
At-Home Smear Tests Poised For Rollout In Major Cervical Cancer Prevention Shift
Motorist Caught At 200km/h On M7 Near Naas Avoids Mandatory Ban By Making €10k Donation To Charity
Local Parents Lose Fuel Allowance Overnight After Unemployed Children Move Back Home, Says Kildare TD
Local Parents Could Be Hit Hard As Creches Threaten To Close Over Funding Crisis