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During the searches a pill manufacturing facility was discovered containing two pill making machines.
During an initial search, Gardaí seized approximately 29kgs of suspected cocaine with an estimated street value of around €2m. €112,050 in cash was also seized.
As part of follow up searches, a pill manufacturing facility was discovered containing two pill making machines.
Cannabis with an estimated street value of €125,000 was seized along with other drug paraphernalia.
A cannabis cultivation facility was also discovered.
Another man and woman have since been released without charge pending a file to the Director of Public Prosecutions. Two other men remain in Garda custody at this time.
Following the arrests Assistant Commissioner Justin Kelly, the officer in charge of the Organised and Serious Crime section remarked:
"I commend the detectives involved in this successful operation to disrupt an organised criminal group exploiting our communities. This work shows our absolute determination to target the activities of key individuals involved in the production and distribution of controlled drugs.
"Illicit pill manufacturing is undertaken in dangerous clandestine facilities with no control measures whatsoever in place, adding to the risk to end users."