Several people have also been injured.
It's been a very busy weekend on the roads this October Bank Holiday weekend.
A man and a woman have died in separate crashes in Cork and Waterford in which several people have been injured.
A man in his twenties died last night after a car he was driving crashed on the N29 in Waterford - a male passenger was injured.
In Cork, a woman in her 80s has died after two cars and a truck crashed on Friday morning on the N22, a man and woman in their fifties, in a second car, were injured.
Gardaí are appealing for witnesses to a serious road crash in Meath last night, after a man in his 20s was hit by a car on the Dublin Road in Navan around 9:30pm.