A number of games are down for decision.
SSE Airtricity Premier Division leaders Shamrock Rovers welcome Drogheda United to Tallaght Stadium for an 8pm kick off tonight.
The other top flight matches begin at 7.45.
Derry City, who lie second, host UCD at the Ryan McBride Brandywell.
It's Dundalk versus Bohemians at Oriel Park,
Sligo Rovers are the visitors to Turner's Cross to play Cork City,
And Damien Duff's Shelbourne play St Patrick's Athletic at Tolka Park.
In the First Division, table toppers Galway United go to Treaty United, it's Waterford away to Finn Harps, Cobh Ramblers at home to Athlone Town, Kerry up against Bray Wanderers and Wexford to play Longford Town.